Europa League and Coppa Italia semi-finalists Atalanta experiment when visiting Monza, so El Bilal Toure and Charles De Ketelaere start.
It kicks off at the U-Power Stadium at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens from today's four Serie A games on the LIVEBLOG.
La Dea are having a remarkable campaign, as they are fresh from knocking Jurgen Klopp's Liverpool out of the Europa League on Thursday and will face Olympique Marseille in the semi-final.
Before that, they also have the second leg of the Coppa Italia semi-final with Fiorentina on Wednesday evening.
Giorgio Scalvini is the only absentee, as Marten de Roon and Davide Zappacosta return from suspension.
There are experiments with what seems to be a 3-4-3 formation, as El Bilal Toure and Ademola Lookman get rare starts.
Monza held fourth-placed Bologna to a 0-0 draw last week and have Jean-Daniel Akpa Akpro suspended, Dany Mota Carvalho, Jose Machin, Davide Bettella and Gianluca Caprari injured.
The good news for coach Raffaele Palladino - who was Gian Piero Gasperini's player and one of many coaches inspired by him - has Luca Caldirola back from suspension.
Monza vs. Atalanta line-ups Monza: Di Gregorio; Birindelli, Izzo, Pablo Mari, Kyriakopoulos; Bondo, Gagliardini; Colpani, Pessina, Zerbin; Djuric
Atalanta: Carnesecchi; Toloi, Hien, Kolasinac; Holm, Pasalic, Ederson, Bakker; De Ketelaere, Toure, Lookman
1st half
2nd half
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