Though, they head into their clash with the Spaniards needing to bounce back from a disappointing and controversial defeat to Newcastle United. As attention turns to Europe, we have rounded up all the latest news and transfer rumours surrounding the Emirates Stadium.
Toney problem Arsenal could face a huge stumbling block in their reported bid to land Ivan Toney in the January transfer window. The Athletic claim the Gunners are interested in the Brentford striker, but Financial Fair Play could ruin their chances.
Arsenal already required a loan-to-buy deal to sign David Raya, and the Bees are unlikely to agree to another similar deal. Toney is said to be keen on a move, but unless the Gunners can raise the large amount of money it would take to sign him, it's unlikely they will find another compromise to make the deal happen.
AS Roma are said to be interested in pulling off a deal for a fringe Arsenal star in January. According to Forza Roma, Roma are interested in landing Jakub Kiwior, who has struggled for game time this season.
Kiwior burst onto the scene last season, but he is not Mikel Arteta's first choice, and he may well want regular game time to continue his progression. Jose Mourinho and Roma are said to be interested in a potential deal, and likely a loan deal. Kiwior already has experience of playing in Italy having played for Spezia before joining the Gunners.
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